Hello. I am working on a hierarchical Bayesian model in a spatial mixed effect setting. Couple of process steps in the hierarchy involve distributions that I know will be computationally challenging ( read not conjugate) and working with data augmentation steps to circumvent them will be computationally expensive. I know STAN will be perfectly suited to handle that part of the hierarchy. I was thus wondering if it is statistically valid to call a STAN sampler update within a Gibbs Sampler. I am thinking like a Metropolis-Hastings in a Gibbs, the STAN will update the parameters in the corresponding process step, but I am not sure if this holds statistically.
Any input as to whether this should be a valid approach and if yes, are there considerations that I need to be aware of? Thank you for your input and time.