# \#torsten

**URL:** https://discourse.mc-stan.org/tag/torsten/242.md

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## [Torsten + Friberg–Karlsson model: ODE solver crashes during warmup](https://discourse.mc-stan.org/t/torsten-friberg-karlsson-model-ode-solver-crashes-during-warmup/40098)

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**Author:** [@gokhale](https://discourse.mc-stan.org/u/gokhale)\
**Replies:** 3\
**Last updated:** [August 21, 2025, 4:15pm UTC](https://discourse.mc-stan.org/t/torsten-friberg-karlsson-model-ode-solver-crashes-during-warmup/40098 "2025-08-21T16:15:08Z")

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Howdy! I am quite excited to start my journey into bayesian PKPD! I’m trying to reproduce the Friberg–Karlsson semi-mechanistic neutropenia model in Stan using Torsten’s pmx\_solve\_group\_rk45 as documented in this wonde…

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## [Error in executing an example in Torsten 0.91.2](https://discourse.mc-stan.org/t/error-in-executing-an-example-in-torsten-0-91-2/40195)

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**Author:** [@Johnny0514](https://discourse.mc-stan.org/u/Johnny0514)\
**Replies:** 7\
**Last updated:** [August 20, 2025, 4:57pm UTC](https://discourse.mc-stan.org/t/error-in-executing-an-example-in-torsten-0-91-2/40195 "2025-08-20T16:57:22Z")

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Dear everyone: I have installed cmdstanr and Torsten 0.91.2. When I tried to execute the test example, the error occurred, as shown below: C:/rtools45/x86\_64-w64-mingw32.static.posix/lib/gcc/x86\_64-w64-mingw32.static.p…

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## [Simultaneously estimating IIV and IOV estimate for first cycle in pharmacokinetic NLME model using Torsten](https://discourse.mc-stan.org/t/simultaneously-estimating-iiv-and-iov-estimate-for-first-cycle-in-pharmacokinetic-nlme-model-using-torsten/38770)

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**Author:** [@marianklose](https://discourse.mc-stan.org/u/marianklose)\
**Replies:** 10\
**Last updated:** [March 10, 2025, 10:20am UTC](https://discourse.mc-stan.org/t/simultaneously-estimating-iiv-and-iov-estimate-for-first-cycle-in-pharmacokinetic-nlme-model-using-torsten/38770 "2025-03-10T10:20:46Z")

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Hello everyone! I am currently setting up Stan with Torsten for a pharmacokinetic NLME (popPK) model. Huge thanks to the Stan and Torsten developers for all their contributions! A bit of context: We work with a NLME mod…

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## [Ensuring convergence without any graphical diagnostics](https://discourse.mc-stan.org/t/ensuring-convergence-without-any-graphical-diagnostics/38864)

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**Author:** [@marianklose](https://discourse.mc-stan.org/u/marianklose)\
**Replies:** 1\
**Last updated:** [February 27, 2025, 9:38am UTC](https://discourse.mc-stan.org/t/ensuring-convergence-without-any-graphical-diagnostics/38864 "2025-02-27T09:38:14Z")

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Hi everyone, I am trying to use stan and torsten (a collection of stan functions to facilitate analysis of pharmacometric data) to individualize parameters of a pharmacokinetic NLME model once measurements become availa…

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## [Dynamically specifying which parameters to estimate in stan](https://discourse.mc-stan.org/t/dynamically-specifying-which-parameters-to-estimate-in-stan/38808)

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**Author:** [@marianklose](https://discourse.mc-stan.org/u/marianklose)\
**Replies:** 4\
**Last updated:** [February 20, 2025, 12:48pm UTC](https://discourse.mc-stan.org/t/dynamically-specifying-which-parameters-to-estimate-in-stan/38808 "2025-02-20T12:48:34Z")

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Hello everyone, I am wondering if it is possible to dynamically specify (e.g., from R) which parameters should be estimated in a Stan model. Use case I am developing an RShiny app that allows physicians/clinicians to i…

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## [Torsten / Stan / Regulatory submissions](https://discourse.mc-stan.org/t/torsten-stan-regulatory-submissions/34707)

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**Author:** [@ericnovik](https://discourse.mc-stan.org/u/ericnovik)\
**Replies:** 4\
**Last updated:** [April 6, 2024, 2:42pm UTC](https://discourse.mc-stan.org/t/torsten-stan-regulatory-submissions/34707 "2024-04-06T14:42:00Z")

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This question is directed at people who work with Torsten and Stan in drug development. We are doing some work for dose justification from the Phase II study to inform dose selection in Phase III, which will be submitte…

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## [Problem installing Torsten 0.90](https://discourse.mc-stan.org/t/problem-installing-torsten-0-90/27585)

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**Author:** [@arya](https://discourse.mc-stan.org/u/arya)\
**Replies:** 16\
**Last updated:** [January 3, 2024, 3:36am UTC](https://discourse.mc-stan.org/t/problem-installing-torsten-0-90/27585 "2024-01-03T03:36:41Z")

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I downloaded Torsten 0.90 earlier today with just a git clone call. I then went into the cmdstan directory and did the usual make build: cd Torsten/cmdstan make build That ran just fine and I got the message that cmdst…