# Pharmacometrician

**URL:** <https://discourse.mc-stan.org/t/pharmacometrician/4342>\
**Category:** Jobs\
**Created:** [May 28, 2018, 5:14pm UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342 "2018-05-28T17:14:29Z")\
**Posts on this page:** 6\
**Page:** 1

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**Author:** ![mercifr1](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/mercifr1/32/9373_2.png) [@mercifr1](https://discourse.mc-stan.org/u/mercifr1)\
**Post date:** [May 28, 2018, 5:14pm UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/1 "2018-05-28T17:14:29Z")

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The Roche Clinical Pharmacology team in Basel is hiring a pharmacometrician to support the Oncology clinical development. The candidate will have 5 or more years of experience in a similar role and will have demonstrated her/his scientific edge through peer-reviewed publications and oral communications in international congresses. Mastering the state-of-the-art modeling and simulation techniques are needed. Programming skills required included: R + NONMEM or Monolix. Bayesian savvy modelers are most welcome! Please express your interest via [https://www.linkedin.com/jobs/view/710683705/](https://www.linkedin.com/jobs/view/710683705/) .

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**Author:** ![Bob\_Carpenter](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/bob_carpenter/32/9230_2.png) [@Bob\_Carpenter](https://discourse.mc-stan.org/u/Bob_Carpenter)\
**Post date:** [June 5, 2018, 2:36am UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/2 "2018-06-05T02:36:02Z")

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@mercifr1: Is there a Stan-related component of this job?

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**Author:** ![mercifr1](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/mercifr1/32/9373_2.png) [@mercifr1](https://discourse.mc-stan.org/u/mercifr1)\
**Post date:** [June 5, 2018, 8:36am UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/3 "2018-06-05T08:36:46Z")

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Yes, there is. Most of the (emprical) disease progression models developed in clinical development by pharmacometrician can/could be coded in rstan. The idea of going bayesian is to leverage as much legacy data as possible to guide the project team in the design and/or analysis of the new clinical trial data. Hope that address your question. Best regards, Francois

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**Author:** ![Bob\_Carpenter](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/bob_carpenter/32/9230_2.png) [@Bob\_Carpenter](https://discourse.mc-stan.org/u/Bob_Carpenter)\
**Post date:** [June 5, 2018, 7:31pm UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/4 "2018-06-05T19:31:37Z")

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Sounds good! Thanks for clarifying.

Stan’s been used in a lot of pharmacometric applications since our first clunky integration of Boost’s ODE solver. We’ve come a long way since then with efficiency and precision, especially for stiff systems and steady-state solutions and efficient linear-system solvers.

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**Author:** ![mercifr1](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/mercifr1/32/9373_2.png) [@mercifr1](https://discourse.mc-stan.org/u/mercifr1)\
**Post date:** [June 6, 2018, 9:01am UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/5 "2018-06-06T09:01:32Z")

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I have been following the development of Stan for a few years now and I have been quite impressed by its progress both in terms of methodology and uptake in various domains such as pharmacometrics. A big thank you to the Stan core team for the time, energy and enthusiasm in proposing this solution.

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**Author:** ![jonah](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.mc-stan.org/jonah/32/200_2.png) [@jonah](https://discourse.mc-stan.org/u/jonah)\
**Post date:** [June 7, 2018, 10:45pm UTC](https://discourse.mc-stan.org/t/pharmacometrician/4342/6 "2018-06-07T22:45:41Z")

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Thanks for sharing that! Hope you find someone good for that job.